0 to 6 months: 4 mg alpha-tocopherol (6 international units [IU]) Conversion rules are as follows: For example, 15 mg of natural alpha-tocopherol would equal 22.4 IU (15 mg x 1.49 IU/mg = 22.4 IU). Gastroenterology 1992;102:2139-42. Vitamin E might also block the formation of carcinogenic nitrosamines formed in the stomach from nitrites in foods and protect against cancer by enhancing immune function [28]. Vitamins have different jobs to help keep the body working properly. 7 to 12 months: 5 mg alpha-tocopherol (7.5 IU) Minerals are elements that our bodies need to function that can be found on the earth and in foods. Scientists are studying vitamin E to understand how it affects health. This content does not have an English version. Cochrane Database Syst Rev 2008;(3):CD002854. Some vitamin E supplements provide other forms of the vitamin, such as gamma-tocopherol, tocotrienols, and mixed tocopherols. One analysis found an increased risk of death at doses of 400 IU/day (form not specified), although the risk began to increase at 150 IU [54]. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. Vitamin-Ereplete endothelial cells lining the interior surface of blood vessels are better able to resist blood-cell components adhering to this surface. Thats because nutrient-dense foods contain other things that are good for you, like fiber. The HOPE and HOPE-TOO trials provide compelling evidence that moderately high doses of vitamin E supplements do not reduce the risk of serious cardiovascular events among men and women >50 years of age with established heart disease or diabetes [23]. Results from an additional 1.5 years of follow-up from this trial (during which the subjects no longer received vitamin E or selenium), showed that the men who had taken the vitamin E had a 17 percent increased risk of prostate cancer compared to men only taking placebos, a statistically significant difference [32]. Just how much vitamin D you need per day, though, depends on many different factors. [, Weitberg AB, Corvese D. Effect of vitamin E and beta-carotene on DNA strand breakage induced by tobacco-specific nitrosamines and stimulated human phagocytes. So far, the only established benefits of vitamin E supplements are in people who have an actual deficiency. WebMD does not provide medical advice, diagnosis or treatment. JAMA 2005;293:1338-47. Tolerable Upper Intake Level (UL): Maximum daily intake unlikely to cause adverse health effects. Average daily recommended amounts are listed below in milligrams (mg). Other research suggests that vitamin E use might increase the risk of death in people with a severe history of heart disease, such as heart attack or stroke. This is the equivalent of 600 IU for those between the ages of 51 and 70 and 800 IUs for those older than 70. The DV for vitamin E is 15 mg for adults and children age 4 years and older [ ]. CONTRAINDICATIONS: None To provide you with the most relevant and helpful information, and understand which The recommended daily value of vitamin E for individuals 14 years of age and older is 15 mg. You can generally get your daily dose of vitamin E through a balanced diet. Online May 5. Different foods in each food group have different nutrients. Use of vitamin E can interact with many conditions. Accessed Aug. 10, 2017. Over 2 years, treatment with vitamin E and selegiline, separately or together, significantly delayed functional deterioration and the need for institutionalization compared to placebo. Vitamins and minerals for women Your body needs vitamins and minerals for good health. This is a general overview of Vitamin E. For more in-depth information, see our health professional fact sheet on Vitamin E. Vitamin E is a fat-soluble nutrient found in many foods. N Engl J Med 2000;342:154-60. It can also be found in green vegetables, like broccoli and spinach. Participants in the studies included in these analyses were typically middle-aged or older and had chronic diseases or related risk factors. Sign up to receive updates and resources delivered to your inbox. [, Morris MC, Evand DA, Bienias JL, Tangney CC, Wilson RS. Includes a variety of vegetables; fruits; grains (at least half whole grains); fat-free and low-fat milk, yogurt, and cheese; and oils. This hypothesis was supported by the results of a clinical trial in 341 patients with Alzheimer's disease of moderate severity who were randomly assigned to receive a placebo, vitamin E (2,000 IU/day dl-alpha-tocopherol), a monoamine oxidase inhibitor (selegiline), or vitamin E and selegiline [47]. Among a group of 5,133 Finnish men and women followed for a mean of 14 years, higher vitamin E intakes from food were associated with decreased mortality from CHD [19]. Magnesium is also present in tap, mineral, or bottled drinking water. privacy practices. Arterioscler Thromb Vasc Biol 2001;21:1320-6. Institute of Medicine. Many claims have been made about vitamin E's potential to promote health and prevent and treat disease. Federal government websites often end in .gov or .mil. A vitamin B-6 deficiency is usually coupled with deficiency in other B vitamins, such as folic acid (vitamin B-9) and vitamin B-12. That is about one teaspoon of salt and includes sodium added during manufacturing or cooking as well as at the table when eating. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Ophthalmology 1998;105:831-6. Evidence that vitamin E could help prevent or delay coronary heart disease (CHD) comes from several sources. Breakfast cereals and other fortified foods often have added magnesium. [, Bostick RM, Potter JD, McKenzie DR, Sellers TA, Kushi LH, Steinmetz KA, et al. This intake level is easy to reach if you consume plenty of whole foods ( 28 ). 15 mcg (600 IU) 71 years and over. 1998 Mar 18;90(6):440-6. The American Cancer Society conducted an epidemiologic study examining the association between use of vitamin C and vitamin E supplements and bladder cancer mortality. What happens if I don't get enough vitamin E? Intake recommendations for vitamin E and other nutrients are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board (FNB) at the Institute of Medicine of The National Academies (formerly National Academy of Sciences) [6]. Read about this topic in Spanish. The body also needs vitamin E to boost its immune system so that it can fight off invading bacteria and viruses. Zinc. The American Heart Association recommends obtaining antioxidants, including vitamin E, by eating a well-balanced diet high in fruits, vegetables, and whole grains rather than from supplements. Research has not found any adverse effects from consuming vitamin E in food [6]. The Age-Related Eye Disease Study (AREDS), a large randomized clinical trial, found that participants at high risk of developing advanced AMD (i.e., those with intermediate AMD or those with advanced AMD in one eye) reduced their risk of developing advanced AMD by 25% by taking a daily supplement containing vitamin E (400 IU [180 mg] dl-alpha-tocopheryl acetate), beta-carotene (15 mg), vitamin C (500 mg), zinc (80 mg), and copper (2 mg) compared to participants taking a placebo over 5 years [41]. Food Sources: Vitamin B3 can be found in some types of nuts, legumes, and grains. In recent years, vitamin E supplements have become popular as antioxidants. Food Sources: Vitamin B6 is found in a wide variety of foods. These are substances that protect cells from damage. Ingrezza, azithromycin, donepezil, memantine, Zithromax, gentamicin, Aricept, acetylcysteine, Creon, ascorbic acid. Vitamin E also has antioxidant properties. Magnesium Dosage: How Much Should You Take per Day? [, Age-Related Eye Disease Study Research Group. Two meta-analyses of randomized trials have also raised questions about the safety of large doses of vitamin E, including doses lower than the UL. The USDA also provides a comprehensive list of foods containing vitamin E arranged by nutrient content and by food name. These amounts are substantially higher than the RDAs. 9 to 13 years: 11 mg alpha-tocopherol (16.4 IU) N Engl J Med 1994;330:1029-35. [, Cavalier L, Ouahchi K, Kayden H, Donato S, Reutenaucer L, Mandel JL, et al. Am J Clin Nutr 2005;81:367-45. N Engl J Med 2005;352:2379-88. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Because insufficient data are available to develop RDAs for infants, AIs were developed based on the amount of vitamin E consumed by healthy breastfed babies. However, the risks and benefits of taking vitamin E supplements are still unclear. Vitamin C and vitamin E supplement use and bladder cancer mortality in a large cohort of US men and women. One study found that women who took vitamin E supplementation during the first 8 weeks of pregnancy had a 1.7 to nine-fold increase in congenital heart defects. Am J Coll Nutr 2006;25:292-9. Tolerable Upper Intake Level (UL): 1000 mg alpha-tocopherol (1500 IU) J Nutr 2006;136:1021-6. BMJ 2007;335:729. Furthermore, use of vitamin E was associated with a significantly increased risk of hemorrhagic stroke. JAMA 2007;298:400-3. JAMA 2013;309:2005-15. Tribble, D.L. Various authors. Natural Standard Patient Monograph: "Vitamin E.", Office of Dietary Supplement: "Vitamin E.". FDA developed DVs to help consumers compare the nutrient contents of foods and dietary supplements within the context of a total diet. If you are a Mayo Clinic patient, this could The risk of developing prostate cancer was also slightly increased in subjects taking vitamin E plus selenium or selenium alone, but the differences were not statistically significant. Primary prevention of age related macular degeneration. Comments: US Recommended Dietary Allowance (RDA): Learn more about vitamins k2 and d3 as well as which . However, one study found a link between the use of vitamin E supplements for 10 years or more and a lower risk of death from bladder cancer. Vitamin B12 - Consumer If you are considering taking a vitamin E supplement, talk to your health care provider first to see if it is right for you. ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. One study of women in Iowa provides evidence that higher intakes of vitamin E from foods and supplements could decrease the risk of colon cancer, especially in women <65 years of age [33]. Study staff members will continue to monitor participants' health for up to 5 more years. It can also be found in cheese, eggs, and different meats. That's a fairly sizable boost over the previous recommendations of 200 IU per day through age 50, 400 IU for ages 51 to 70, and 600 IU for ages over 70. Most vitamin-E-only supplements provide 67 mg (100 IU of natural vitamin E) of the nutrient. Frank vitamin E deficiency is rare and overt deficiency symptoms have not been found in healthy people who obtain little vitamin E from their diets [6]. Determine your RDA and add a supplement if necessary to avoid calcium deficiency. Vitamin E Information | Mount Sinai - New York Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial. Long-term intakes above the UL increase the risk of adverse health effects [6]. *DV = Daily Value. We encourage you to talk to your health care providers (doctor, registered dietitian, pharmacist, etc.) You can get calcium from milk and other dairy, some forms of tofu, dark-green leafy vegetables, soybeans, canned sardines and salmon with bones, and calcium-fortified foods. Two clinical trials have found an increased risk of hemorrhagic stroke in participants taking alpha-tocopherol; one trial included Finnish male smokers who consumed 50 mg/day for an average of 6 years [53] and the other trial involved a large group of male physicians in the United States who consumed 400 IU (180 mg) of synthetic vitamin E every other day for 8 years [26]. Food Labeling: Revision of the Nutrition and Supplement Facts Labels and Serving Sizes of Foods That Can Reasonably Be Consumed at One Eating Occasion; Dual-Column Labeling; Updating, Modifying, and Establishing Certain Reference Amounts Customarily Consumed; Serving Size for Breath Mints; and Technical Amendments; Proposed Extension of Compliance Dates. Each vitamin and mineral has a specific RDA. However, two randomized controlled trials in which participants took supplements of vitamin E (500 IU/day [335 mg] d-alpha-tocopherol in one study [39] and 111 IU/day (50 mg) dl-alpha-tocopheryl acetate combined with 20 mg/day beta-carotene in the other [40]) or a placebo failed to show a protective effect for vitamin E on AMD. Explore details about the following vitamins and minerals and recommended amounts for older adults: Vitamin A | Vitamin B1 (Thiamin) | Vitamin B2 (Riboflavin) | Vitamin B3 (Niacin) | Vitamin B6 | Vitamin B12 | Vitamin C | Calcium | Vitamin D | Vitamin E | Folate | Vitamin K | Magnesium | Potassium | Sodium. Diet in the epidemiology of postmenopausal breast cancer in the New York State Cohort. The body forms ROS endogenously when it converts food to energy, and antioxidants might protect cells from the damaging effects of ROS. Participants taking vitamin E, however, were 13% more likely to experience, and 21% more likely to be hospitalized for, heart failure, a statistically significant but unexpected finding not reported in other large studies. Last updated on Mar 30, 2023. Food Labeling: Revision of the Nutrition and Supplement Facts Labels. Scientists are investigating whether, by limiting free-radical production and possibly through other mechanisms, vitamin E might help prevent or delay the chronic diseases associated with free radicals. The 12 Best Supplements, According to a Dietitian . Cardiovascular studies also suggest that patients with diabetes or cardiovascular disease who take natural vitamin E at 400 IU per day have an increased risk of heart failure and heart failure-related hospitalization. An official website of the United States government. In the Women's Health Study, in which healthy women 45 years of age received either 600 IU of natural vitamin E (402 mg) every other day or a placebo for 10 years, the supplement did not reduce the risk of developing any form of cancer [25]. The body hydrolyzes and absorbs these esters (alpha-tocopheryl acetate and succinate) as efficiently as alpha-tocopherol [6]. Picking an assortment within every food group throughout the week will help you get many nutrients. Also, talk to your doctor about vitamin E use if you're about to have or you just had a procedure to open blocked arteries and restore normal blood flow to your heart muscle (angioplasty). [, Traber MG. Heart disease and single-vitamin supplementation. . Vitamin D - Mayo Clinic Overall, the available evidence is inconsistent with respect to whether vitamin E supplements, taken alone or in combination with other antioxidants, can reduce the risk of developing AMD or cataracts. But the best research finds no benefit. 0-12 months. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. Most older adults can get all the nutrients they need from foods. Many people use vitamin E supplements in the hopes that the vitamin's antioxidant properties will prevent or treat disease. Vitamin E and donepezil for the treatment of mild cognitive impairment. Join the ODS Email List. The FNB has established ULs for vitamin E based on the potential for hemorrhagic effects (see Table 3). Further research is needed to determine whether supplemental vitamin E has any protective value for younger, healthier people at no obvious risk of CHD. In most Americans diets, sodium primarily comes from salt (sodium chloride). The liver preferentially resecretes only alpha-tocopherol via the hepatic alpha-tocopherol transfer protein [1]; the liver metabolizes and excretes the other vitamin E forms [2]. Most people can easily get this in their regular diet without synthetic vitamin A . What kinds of vitamin E dietary supplements are available? Not only did the supplements provide no cardiovascular benefits, but all-cause mortality was significantly higher in the women taking the supplements. Division of Behavioral and Social Research, Division of Geriatrics and Clinical Gerontology, Training Opportunities for Special Populations, Alzheimer's Disease and Related Dementias Funding Announcements, Alzheimers & Related Dementias Press Kit, National Advisory Council on Aging (NACA), Advances in Aging and Alzheimer's Research, U.S. Department of Health & Human Services (HHS), Participating in Activities You Enjoy As You Age, Getting Your Affairs in Order Checklist: Documents to Prepare for the Future, Healthy Meal Planning: Tips for Older Adults, How Much Should I Eat? One prospective cohort study found that lens clarity was superior in participants who took vitamin E supplements and those with higher blood levels of the vitamin [43]. 1. The diets of most Americans provide less than the recommended amounts of vitamin E. Nevertheless, healthy people rarely show any clear signs that they are not getting enough vitamin E (see next question for information on the signs of vitamin E deficiency). Your body also uses vitamin A to make pigments for your retinas to work well, and moisture for your corneas. [, Klein EA, Thompson Jr. IM, Tangen CM, Crowley JJ, Lucia MS, Goodman PJ, et al. Vitamins and their benefits Here's what vitamins and minerals you should consider taking. Vitamin E deficiency can cause nerve pain (neuropathy). For more information about building a healthy dietary pattern, see the Dietary Guidelines for Americans and the U.S. Department of Agricultures MyPlate. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. Men: 16 mg/day; Women: 14 mg/day; . Evidence to date is insufficient to support taking vitamin E to prevent cancer. [, Dietrich M, Traber MG, Jacques PF, Cross CE, Hu Y, Block G. Does -tocopherol play a role in the primary prevention of heart disease and cancer? Vitamin E deficiency and impaired cellular immunity related to intestinal fat malabsorption. [, Knekt P, Reunanen A, Jarvinen R, Seppanen R, Heliovaara M, Aromaa A. Antioxidant vitamin intake and coronary mortality in a longitudinal population study. How Much Vitamin D Do You Need Each Day? Calcium and Vitamin D Requirements Some research has shown that high-dose vitamin E might delay the progression of Alzheimer's disease in people who have been diagnosed with mild to moderate Alzheimer's disease. No differences were found among groups in the incidence of lung or colorectal cancers or all cancers combined. The recommended daily amount of vitamin E for adults is 15 milligrams a day. Vitamin E and cognitive decline in older persons. How much vitamin E do I need? Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? In a clinical trial involving 29,133 male smokers, men randomly assigned to take daily supplements of 111 IU of synthetic vitamin E (50 mg, as dl-alpha-tocopheryl acetate) for 58 years had 32% fewer prostate cancers compared to subjects who did not take the supplements [30]. One study of approximately 90,000 nurses found that the incidence of heart disease was 30% to 40% lower in those with the highest intakes of vitamin E, primarily from supplements [18]. These findings are supported by evidence from the Women's Angiographic Vitamin and Estrogen study, in which 423 postmenopausal women with some degree of coronary stenosis took supplements with 400 IU vitamin E (form not specified) and 500 mg vitamin C twice a day or placebo for >4 years [24]. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). So far, the research provides little evidence that taking vitamin E supplements can help healthy people or people with mild mental functioning problems to maintain brain health. Acta Ophthalmol Scand 1997;75:634-40. Have a question? Several observational studies have revealed a potential relationship between vitamin E supplements and the risk of cataract formation. Greenberg ER. Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. Vitamin E deficiency is very rare in healthy people. These values, which vary by age and gender, include: The FNB's vitamin E recommendations are for alpha-tocopherol alone, the only form maintained in plasma. A prospective study on supplemental vitamin E intake and risk of colon cancer in women and men. UL: 300 mg alpha-tocopherol (450 IU) Video of the Day How much vitamin E do you need? JAMA 2005;293:1387-90. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. If you have high blood pressure or prehypertension, limiting sodium intake to 1,500 mg per day, about 2/3 teaspoon of salt, may be helpful. Join the ODS Email List. Page last reviewed: 03 August 2020 Among people with AMD who were at high risk of developing advanced AMD, a supplement containing large doses of vitamin E combined with other antioxidants, zinc, and copper showed promise for slowing down the rate of vision loss. BMJ 2007;335:755. Gao X, Wilde PE, Lichtenstein AH, Bermudez OI, Tucker KL. Content reviewed: Find information on some of the essential vitamins recommended for older adults and how to get the recommended amount within your diet. If you take vitamin A for its antioxidant properties, keep in mind that the supplement might not offer the same benefits as naturally occurring antioxidants in food. 1 IU synthetic vitamin E (commonly labeled dl-alpha-tocopherol) = 0.45 mg alpha tocopherol. In another study, long-term use of vitamin E supplements was associated with slower progression of age-related lens opacification [44]. By the way, doctor: What's the right amount of vitamin C for me? Although the effect of vitamin E on the risk of noncommunicable chronic diseases is controversial, it is interesting to note that in the Women's Health Study supplementation with 600 IU vitamin E (-tocopherol) every other day for an average of 10.1 y significantly reduced the risk of major cardiovascular events only in those >65 y of age (26% . This collection of antioxidant ingredients blunted the rise in high-density lipoprotein (HDL) cholesterol levels, especially levels of HDL2, the most cardioprotective HDL component, among people treated with a combination of simvastatin (brand name Zocor) and niacin [62,63]. This fact sheet by the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) provides information that should not take the place of medical advice. [, Brion LP, Bell EF, Raghuveer TS. March 22, 2021 [, Jialal I, Devaraj S. Vitamin E supplementation and cardiovascular events in high-risk patients. The recommended daily amount of vitamin A is 900 micrograms (mcg) for adult men and 700 mcg for adult women. Estimated Average Requirement (EAR): Average daily level of intake estimated to meet the requirements of 50% of healthy individuals; usually used to assess the nutrient intakes of groups of people and to plan nutritionally adequate diets for them; can also be used to assess the nutrient intakes of individuals. However, participants in these studies have been largely middle-aged or elderly individuals with demonstrated heart disease or risk factors for heart disease. Quantity and Quality. Huang HY, Caballero B, Chang S, Alberg A, Semba R, Schneyer C, et al. N Engl J Med 1997;336:1216-22. Some researchers have suggested that understanding the potential utility of vitamin E in preventing CHD might require longer studies in younger participants taking higher doses of the supplement [27]. Whenever you add salt to your food, you're adding sodium. Vitamin A Dosage Guide + Max Dose, Adjustments - Drugs.com The Benefits and Risks of Taking Vitamin A [, Jacques PF, Taylor A, Moeller S, Hankinson SE, Rogers G, Tung W, et al. Consumer Datos en espaol Health Professional Other Resources Table of Contents What is vitamin E and what does it do? What are the side effects of taking vitamin E? Several observational studies have associated lower rates of heart disease with higher vitamin E intakes. National Institutes of Health Some people with abetalipoproteinemia, a rare inherited disorder resulting in poor absorption of dietary fat, require enormous doses of supplemental vitamin E (approximately 100 mg/kg or 510 g/day) [1]. Vitamin A - Mayo Clinic [, Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. 4mg a day for men; 3mg a day for women; . Mayo Clinic Q and A: How much vitamin D do I need? Vitamin K: Uses, Deficiency, Dosage, Food Sources, and More 888-463-6332druginfo@fda.hhs.govwww.fda.gov, Dietary Guidelines for Americans The Several studies have examined whether vitamin E intake and/or supplemental vitamin E affects the risk of developing prostate cancer. Parenting is one of the most complex and challenging jobs you'll face in your lifetime -- but also the most rewarding. Vitamins have different jobs to help keep the body working properly. Vitamin A: Benefits, Deficiency, Toxicity, and More - Healthline Applies to the following strengths: with mixed tocopherols 400 intl units; alpha 100 intl units; with mixed tocopherols 200 intl units; with mixed tocopherols 1000 intl units; 600 intl units; 400 intl units; 100 intl units; 15 intl units/0.3 mL; 180 mg; 200 intl units; 1000 intl units; dl-alpha 400 intl units; alpha 1000 intl units; d-alpha 200 intl units; d-alpha 400 intl units; dl-alpha 600 intl units; 90 mg; d-alpha tocopherol with tocopherols and tocotrienols; 75 intl units (50 mg)/mL; 33.5 mg; 100 intl units/0.25 mL; dl-alpha1000 intl units, Abetalipoproteinemia: approximately 100 mg/kg or 5 to 10 grams alpha-tocopherol per day. Have a question? Hayden, K.M. However, among current smokers and men who had quit, vitamin E intakes of more than 400 IU/day (form not specified) were associated with a statistically significant 71% reduction in the risk of advanced prostate cancer. Converting from international units (IU) to mg: 1 IU natural vitamin E (commonly labeled d-alpha-tocopherol) = 0.67 mg alpha tocopherol. Then add 300 to account for all the calcium you would get from the rest of your diet. about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. The U.S. Food and Drug Administration (FDA) required manufacturers to use these new labels starting in January 2020, but companies with annual sales of less than $10 million may continue to use the old labels that list vitamin E in international units (IUs) until January 2021 [8]. For more information about building a healthy dietary pattern, refer to the Dietary Guidelines for Americans and the U.S. Department of Agriculture's MyPlate. The implications of these analyses for the potential adverse effects of high-dose vitamin E supplements are unclear [56-59]. Treatment of dementia. More research is needed to identify the role of vitamin E, if any, in the management of cognitive impairment [52]. Annu Rev Nutr 2007;27:347-62. For example, the Heart Outcomes Prevention Evaluation (HOPE) study, which followed almost 10,000 patients at high risk of heart attack or stroke for 4.5 years [21], found that participants taking 400 IU/day of natural vitamin E (268 mg) experienced no fewer cardiovascular events or hospitalizations for heart failure or chest pain than participants taking a placebo. You can get recommended amounts of vitamin E by eating a variety of foods including the following: Vitamin E supplements come in different amounts and forms. NIA scientists and other experts review this content to ensure it is accurate and up to date. How much sodium is okay? [, Jacobs EJ, Henion AK, Briggs PJ, Connell CJ, McCullough ML, Jonas CR, et al. Vitamin E dietary supplements can interact or interfere with certain medicines that you take. However, a clinical trial in primarily healthy older women who were randomly assigned to receive 600 IU (402 mg) d-alpha-tocopherol every other day or a placebo for 4 years found that the supplements provided no apparent cognitive benefits [49].
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